Food and Drug Administration, Center for Drug Evaluation and Research. And while it supposed to stay in your stomach, it sometimes doesn. How should you take Protonix? Protonix may be taken with or without food. It is prescribed to heal condition called erosive esophagitis severe inflammation of the passage to the stomach brought on by persistent backflow of stomach acid gastroesophageal reflux disease. Important Safety Information In clinical trials, the most frequently reported side effects with PROTONIX Delayed-Release Tablets were headache, diarrhea, and gas. The overall incidence of major adverse cardiovascular events was 51 percent higher in those taking Plavix and PPI than in those taking Plavix alone, Stanek said. Pantoprazole excretion in human milk has protonix acquistare senza perscription been detected in study of single nursing mother after single 40 mg oral dose.